Some items and runewords won't drop or cannot be socketed in non-ladder. These are known as Diablo 2 Ladder items. Moreover, runes are very popular because if you insert some specific Rune combinations (known as Runewords) into some specific items in the right order, these items will provide much more powerful bonuses.Īlso, some types of items are available only in Diablo 2 Ladder mode. Runes are useful for creating some Crafted Items too. Runes look like small magical stones and you can place them into a Socketed Item to enchant it with powerful bonuses.